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International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of oral administration of polyherbal combination (PHC) on relative organ weight (g) of mice

From: An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin

Organ

Relative organ weight (gm)

Distilled water

250 mg/kg/day

500 mg/kg/day

1000 mg/kg/day

2000 mg/kg/day

NCX

TX1

TX2

TX3

TX4

Brain

1.874 ± 0.220

1.816 ± 0.208

1.795 ± 0.108

1.804 ± 0.161

1.842 ± 0.142

Heart

0.875 ± 0.040

0.85 ± 0.005

0.851 ± 0.068

0.851 ± 0.078

0.879 ± 0.069

Kidney (L + R)

1.249 ± 0.075

1.222 ± 0.046

1.4 ± 0.253

1.214 ± 0.113

1.26 ± 0.117

Liver

6.024 ± 0.431

5.91 ± 0.074

5.822 ± 0.348

5.793 ± 0.433

6.059 ± 0.470

Lung

1.293 ± 0.068

1.294 ± 0.043

1.274 ± 0.063

1.249 ± 0.098

1.303 ± 0.092

  1. The values were depicted as means ± SD for 5 mice per group. Statistically significant differences between groups were measured using one-way ANOVA with nonparametric paired t-test. The values in different treated groups were found to be non-significant (p > 0.05) when compared to normal control group (NCX)