Table 4 Changes in body weight, relative liver and kidney weight of male Wistar rats administered with lead acetate and treated with methanol and methanol/acetone phenolic-rich extracts of N. latifolia fruit

Control (2 mL/kg bw. Normal Saline)

126.75 ± 0.75

140.50 ± 0.87^d

13.75 ± 0.75^d

10.86 ± 0.61^d

Silymarin (100 mg/kg bw.)

126.00 ± 0.82

134.25 ± 0.85^c

8.25 ± 0.25^c

6.55 ± 0.20^c

Untreated (2 mL/kg bw. Normal Saline)

124.75 ± 1.18

124.50 ± 0.87^a

− 0.25 ± 1.11^a

−0.18 ± 0.88^a

150 mg/kg bw. MPR NLF

123.75 ± 0.95

129.00 ± 0.71^b

5.25 ± 0.75^b

4.25 ± 0.63^b

300 mg/kg bw. MPR NLF

125.50 ± 1.50

133.50 ± 1.76^c

8.00 ± 0.41^c

6.37 ± 0.29^c

150 mg/kg bw. MAPR NLF

125.25 ± 1.93

131.75 ± 2.02^bc

6.50 ± 0.87^b

5.19 ± 0.72^b

300 mg/kg bw. MAPR NLF

125.50 ± 1.44

138.25 ± 1.57^d

12.75 ± 0.85^d

10.17 ± 0.69^d