International Journal of Phytomedicine and Phytotherapy
From: Toxicological studies of aqueous and ethanol leaf extract of Spondias purpurea (red plum) in rats
Histopathological changes | C | AQ extract (mg/kg) 5,001,000 1500 | ET extract (mg/kg) 5,001,000 1500 | ||||
---|---|---|---|---|---|---|---|
Congestion | – | + | + | + | + | ++ | + |
Necrosis of renal tubular epithelium | – | + | + | + | + | + | + |
Widened Bowman’s space | – | + | + | + | + | + | + |
Collapsed renal tubules | – | – | – | – | – | – | + |
Mononuclear cellular infiltration | – | – | + | + | + | – | + |
Congested with Hemosiderosis | – | – | – | – | – | – | + |
Adhesion of the parietal layer of the glomerulus to the Bowman’s space | – | – | + | + | – | + | + |