Fig 3From: Hepatoprotective effect of oral application of a silymarin extract in carbon tetrachloride-induced hepatotoxicity in ratsEffect of the silymarin extract (SE) on pro-inflammatory and pro-fibrogenic gene expression in activated hepatic stellate cells (HSC). Primary activated human HSC were stimulated in vitro for 24 h with SE in the indicated doses. a Analysis of mRNA levels of MCP-1, b TGFß1 and d Coll-I by quantitative RT PCR. c Analysis of MCP-1 protein levels in the cell culture supernatant by ELISA. (*: p < 0.05)Back to article page