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International Journal of Phytomedicine and Phytotherapy

Fig 3 | Clinical Phytoscience

Fig 3

From: Hepatoprotective effect of oral application of a silymarin extract in carbon tetrachloride-induced hepatotoxicity in rats

Fig 3

Effect of the silymarin extract (SE) on pro-inflammatory and pro-fibrogenic gene expression in activated hepatic stellate cells (HSC). Primary activated human HSC were stimulated in vitro for 24 h with SE in the indicated doses. a Analysis of mRNA levels of MCP-1, b TGFß1 and d Coll-I by quantitative RT PCR. c Analysis of MCP-1 protein levels in the cell culture supernatant by ELISA. (*: p < 0.05)

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