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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of M.africana on hematological and biochemical measurements in male Wistar rats at 48 h

From: Acute toxicity studies of Myrsine africana aqueous seed extract in male Wistar rats on some hematological and biochemical parameters

Parameter Control 1000 mg/ 5000 mg
WBC (103/μL) 10.1 ± 2.7 10.9 ± 5.3 8.1 ± 1.5
RBC (106xμL) 5.6 ± .22 6.1 ± 1.3 *7.6 ± 9.8
PCV (%) 35.1 ± 1.5 34.3 ± 8.1 *44.1 ± 5.3
Hb (g/dL) 14.0 ± .81 13.9 ± 2.5 14.5 ± .32
MCV(fL) 63.9 ± .60 57 ± 2.7 59.7 ± 1.2
MCH(pg) 24.0 ± 1.2 24.3 ± 1.2 22.3 ± 3.0
MCHC (g/dL) 38.5 ± .91 43.5 ± 3.2 32.4 ± 5.3
THROMB (103/μL) 336.2 ± 59.8 441 ± 99 419 ± 8.9
AST (U/L) 45.6 ± 15.1 41. 6 ± 7.3 38.1 ± 12.0
ALAT(U/L) 46.4 ± 2.4 42.1 ± 4.9 44.6 ± 4.2
Total proteins (g/dL) 7.7 ± 5.2 7.5 ± .86 8.2 ± .9
Creatinine (mg/dL) 1.7 ± .36 4.2 ± 4.5 *15.6 ± 2.1
Urea (mg/dL) 42.9 ± 3.7 46.8 ± 3.8 46.8 ± 8.0
  1. *Significantly different