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International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of M.africana on hematological and biochemical measurements in male Wistar rats at day14

From: Acute toxicity studies of Myrsine africana aqueous seed extract in male Wistar rats on some hematological and biochemical parameters

Parameter Control 1000 mg/kg/bwt 5000 mg/kg bwt
WBC (103/μL) 9.1 ± .34 12.27 ± 1.4 18 ± 3.1
RBC (106xμL) 5.7 ± .57 6.37 ± .31 6.3 ±. 62
PCV (%) 35.2 ± 3.1 38.9 ± 1.7 37.3 ± 2.6
Hb(g/dL) 12.8 ± 1.5 15.2 ± .94 15.2 ±. 71
MCV(fL) 63 ± 1.4 59.9 ± .78 60.1 ± 4.0
MCH(pg.) 23.8±. 82 23.2 ± .61 22.4 ± 4.7
MCHC (g/dL) 38 ± 1.1 39.4 ± 1.2 39 ± 1.4
Thromb. (103/μL) 186 ± 20 288 ± 44.7 *564 ± 71
AST (U/L) 34.46 ± 7.5 *57.2 ± 5.9 *55.4 ± 4.1
ALAT(U/L) 44.7 ± 6.4 45 ± 4.6 48.1 ± 5.9
Total proteins(g/dL) 8.7 ± 2.2 6.5 ± .76 8.7 ± 1.8
Creatinine (mg/dL 1.8 ± 1.3 1.9 ± .78 1.9 ± .22
Urea (mg/dL) 42.8 ± 6.2 *21.8 ± 5.0 *27.8 ± 4.7
  1. *Significantly different