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International Journal of Phytomedicine and Phytotherapy

Clinical Phytoscience Cover Image
Fig. 7 | Clinical Phytoscience

Fig. 7

From: Black cohosh (Cimicifuga racemosa) is a non-estrogenic alternative to hormone replacement therapy

Fig. 7

Luteinizing hormone release in ovx rats. a Control, application of 2 % Cremophor; (b) ovx rats, application of E2 3.5 μg iv. Pulsatile LH release by the pituitary occurs at the same frequency as the subcutaneously measured temperature pulses (hot flushes). This suggests a common hypothalamic mechanism that generates hot flushes and LH pulses (a). Pulsatile LH release is strongly inhibited by an injection of estradiol (b). Appl: Application; E2: Estradiol; iv: intravenous

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