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International Journal of Phytomedicine and Phytotherapy

Fig. 8 | Clinical Phytoscience

Fig. 8

From: Black cohosh (Cimicifuga racemosa) is a non-estrogenic alternative to hormone replacement therapy

Fig. 8

Displacement curves of the BNO 1055 CR extract and the reference compounds dopamine (DA), norepinephrine (NE) or serotonin 5-HT in receptor binding assays (RBA). a Norepinephrine RBA; (b) Dopamine RBA; (c) Serotonin RBA. The receptor preparations originate from rat brain tissue. Radioactively labeled DA, NE and 5-HT bind to their respective receptors and substances with affinities to the respective receptor displace the radiolabeled neurotransmitter. This indicates that the BNO 1055 CR extract contains NE-, DA- and 5HT- mimetic substances. CR: Cimicifuga racemosa

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