A preliminary evaluation of cytotoxicity, antihyperglycemic and antinociceptive activity of Polygonum hydropiper L. ethanolic leaf extract

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of crude ethanolic extract of P. hydropipper L. aerial parts (EEPHL and EEPHS) on blood glucose level in hyperglycemic mice following two hours of glucose loading. All administrations were made orally

Treatment	Dose (mg/kg body weight)	Blood glucose level (mmol/l)	% lowering of blood glucose level
Control	10 ml	5.32 ± 0.32	--
Glibenclamide	10 mg	3.08 ± 0.08	42.1*
EEPHL	50 mg	2.72 ± 0.03	48.8*
EEPHL	100 mg	2.58 ± 0.06	51.5*
EEPHL	200 mg	2.44 ± 0.05	54.1*
EEPHL	400 mg	2.22 ± 0.07	58.2*
EEPHS	400 mg	5.24 ± 0.07	1.5

Values represented as mean ± SEM, (n = 5); *P < 0.05; significant compared to hyperglycemic control animals