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International Journal of Phytomedicine and Phytotherapy

Table 4 Antinociceptive effect of crude ethanolic leaf extract of P. hydropipper L. in acetic acid-induced pain model mice. All administrations (aspirin and extract) were made orally

From: A preliminary evaluation of cytotoxicity, antihyperglycemic and antinociceptive activity of Polygonum hydropiper L. ethanolic leaf extract

Treatment Dose (mg/kg body weight) Mean number of abdominal writhings % inhibition
Control 10 ml 15.6 ± 0.75 --
Aspirin 200 mg 9.2 ± 0.66 41.02*
Aspirin 400 mg 4.8 ± 0.37 69.23*
EEPHL 50 mg 13.4 ± 0.51 14.10*
EEPHL 100 mg 12.8 ± 0.37 17.95*
EEPHL 200 mg 11 ± 0.71 29.49*
EEPHL 400 mg 9.2 ± 0.75 41.02*
  1. Values represented as mean ± SEM, (n = 5); *P < 0.05; significant compared to control