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International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of B.Vulgaris on biochemical parameters of normoglycemic and STZ-induced diabetic rats

From: Effects of an ethanolic extract of Berberis vulgaris fruits on hyperglycemia and related gene expression in streptozotocin-induced diabetic rats

Experimental groupsa Fasting Blood Glucose (FBG) (mmol/L) Insulin (μU/ml) Malondialdehyde (MDA) (μmol/L) Total antioxidant (FRAP) (μmol/L) Number of pancreatic islets (cm−2)
Normoglycemic Control 7.6 ± 0.4b* 15.2 ± 0.7* 1.27 ± 0.5* 780 ± 14* 43 ± 3.5*
Diabetic Control 25 ± 1.2 7.4 ± 0.3 4.3 ± 0.7 550 ± 21 13 ± 1.8
Diabetic + B.vulgaris (25 mg/kg body mass) 12.9 ± 0.7* 9.2 ± 0.5 2.9 ± 0.3* 655 ± 18* 18 ± 1.9*
Diabetic + B.vulgaris (100 mg/kg body mass) 8.2 ± 0.4* 11.9 ± 0.6* 2.1 ± 0.2* 760 ± 16* 29 ± 2.6*
Diabetic + Glibenclamide (0.6 mg/kg body mass) 7.8 ± 0.8* 13.4 ± 0.4* 1.85 ± 0.1* 810 ± 15* 34 ± 0.4*
  1. aFor details of experimental conditions see the text
  2. bData are expressed as mean ± SD of 8 rats in each group. In each column
  3. *was considered significant at P < 0.05 when compared with the diabetic control group