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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of B.Vulgaris on biochemical parameters of normoglycemic and STZ-induced diabetic rats

From: Effects of an ethanolic extract of Berberis vulgaris fruits on hyperglycemia and related gene expression in streptozotocin-induced diabetic rats

Experimental groupsa

Fasting Blood Glucose (FBG) (mmol/L)

Insulin (μU/ml)

Malondialdehyde (MDA) (μmol/L)

Total antioxidant (FRAP) (μmol/L)

Number of pancreatic islets (cm−2)

Normoglycemic Control

7.6 ± 0.4b*

15.2 ± 0.7*

1.27 ± 0.5*

780 ± 14*

43 ± 3.5*

Diabetic Control

25 ± 1.2

7.4 ± 0.3

4.3 ± 0.7

550 ± 21

13 ± 1.8

Diabetic + B.vulgaris (25 mg/kg body mass)

12.9 ± 0.7*

9.2 ± 0.5

2.9 ± 0.3*

655 ± 18*

18 ± 1.9*

Diabetic + B.vulgaris (100 mg/kg body mass)

8.2 ± 0.4*

11.9 ± 0.6*

2.1 ± 0.2*

760 ± 16*

29 ± 2.6*

Diabetic + Glibenclamide (0.6 mg/kg body mass)

7.8 ± 0.8*

13.4 ± 0.4*

1.85 ± 0.1*

810 ± 15*

34 ± 0.4*

  1. aFor details of experimental conditions see the text
  2. bData are expressed as mean ± SD of 8 rats in each group. In each column
  3. *was considered significant at P < 0.05 when compared with the diabetic control group
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