International Journal of Phytomedicine and Phytotherapy
Table 2 Summary of dose-dependent effects of silymarin on serum markers and on tissue biochemical variables in rats (derived data as highest percent change [67, 68])
From: The potential of silymarin for the treatment of hepatic disorders
| Â | ALT | AST | ALP | Bilirubin |
Paracetamol | −48 % | −80 % | −39 % | −62 % |
CCl4 | −45 % | −46 % | −47 % | −31 % |
|  | TBARS | GSH | Nitrite/Nitrate | Na + K+ ATPase |
Paracetamol | −70 % | +100 % | −33 % | +123 % |
CCl4 | −50 % | +164 % | −28 % | +158 % |