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International Journal of Phytomedicine and Phytotherapy

Table 2 Summary of dose-dependent effects of silymarin on serum markers and on tissue biochemical variables in rats (derived data as highest percent change [67, 68])

From: The potential of silymarin for the treatment of hepatic disorders

  ALT AST ALP Bilirubin
Paracetamol −48 % −80 % −39 % −62 %
CCl4 −45 % −46 % −47 % −31 %
  TBARS GSH Nitrite/Nitrate Na + K+ ATPase
Paracetamol −70 % +100 % −33 % +123 %
CCl4 −50 % +164 % −28 % +158 %