International Journal of Phytomedicine and Phytotherapy
Table 1 Effect of therapy with prednisolone, CAN and their combination on the main immunological markers of autoimmune renal pathology (mean ± SEM, n = 8 in each group)
From: Efficiency of Canephron N in complex treatment of experimental heymann glomerulonephritis
Groups of animals | Study parameters | |||
|---|---|---|---|---|
CD3+, ×109/L | CD4 + CD3+, % | CD8 + CD3+, % | Immune-regulatory index (CD4+/CD8+) | |
Healthy | 5,7 ± 0,1 | 55,2 ± 0,9 | 44,1 ± 1,1 | 1,26 ± 0,04 |
AIG | 5,5 ± 0,1 | 51,0 ± 1,6* | 25,6 ± 1,3* | 2,01 ± 0,07* |
AIG + Prednisolone | 4,9 ± 0,1 */† | 52,1 ± 1,1 | 30,2 ± 1,3*/† | 1,74 ± 0,07*/† |
AIG + CAN | 5,6 ± 0,1# | 51,9 ± 1,2 | 26,2 ± 1,4* | 2,00 ± 0,09* |
AIG + Prednisolone + CAN | 5,1 ± 0,1*/† | 54,2 ± 0,7 | 34,5 ± 0,6*/†/# | 1,58 ± 0,04*/† |