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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of therapy with prednisolone, CAN and their combination on biochemical blood parameters in autoimmune glomerulonephritis (mean ± SEM, n = 8 in each group)

From: Efficiency of Canephron N in complex treatment of experimental heymann glomerulonephritis

Groups of animals Study parameters
BUN, mmol/L Creatinine, μmol/L Cholesterol, mmol/L AOPP, μmol/L РСО, nmol/mg
Healthy 4,3 ± 0,2 50,4 ± 3,5 1,22 ± 0,08 58,0 ± 10,1 0,79 ± 0,12
AIG 9,3 ± 0,6* 168,4 ± 11,9* 2,59 ± 0,17* 238,1 ± 13,1* 3,84 ± 0,31*
AIG + Prednisolone 6,4 ± 0,5*/† 101,3 ± 10,8*/† 1,97 ± 0,15*/† 154,6 ± 11,0*/† 2,59 ± 0,18*/†
AIG + CAN 8,6 ± 0,8*# 118,1 ± 9,3*/† 2,39 ± 0,23* 204,0 ± 20,3*/# 3,38 ± 0,17*/#
AIG + Prednisolone + CAN 5,3 ± 0,4*/† 86,2 ± 6,1*/† 1,72 ± 0,11*/† 105,7 ± 11,98*/†/# 1,99 ± 0,11*/†/#
  1. * -differences are significant vs, healthy rats, р ≤ 0,05
  2. † −differences are significant vs, AIG group, р ≤ 0,05
  3. # -differences are significant vs, Prednisolone group, p ≤ 0,05