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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of therapy with prednisolone, CAN and their combination on biochemical blood parameters in autoimmune glomerulonephritis (mean ± SEM, n = 8 in each group)

From: Efficiency of Canephron N in complex treatment of experimental heymann glomerulonephritis

Groups of animals

Study parameters

BUN, mmol/L

Creatinine, μmol/L

Cholesterol, mmol/L

AOPP, μmol/L

РСО, nmol/mg

Healthy

4,3 ± 0,2

50,4 ± 3,5

1,22 ± 0,08

58,0 ± 10,1

0,79 ± 0,12

AIG

9,3 ± 0,6*

168,4 ± 11,9*

2,59 ± 0,17*

238,1 ± 13,1*

3,84 ± 0,31*

AIG + Prednisolone

6,4 ± 0,5*/†

101,3 ± 10,8*/†

1,97 ± 0,15*/†

154,6 ± 11,0*/†

2,59 ± 0,18*/†

AIG + CAN

8,6 ± 0,8*#

118,1 ± 9,3*/†

2,39 ± 0,23*

204,0 ± 20,3*/#

3,38 ± 0,17*/#

AIG + Prednisolone + CAN

5,3 ± 0,4*/†

86,2 ± 6,1*/†

1,72 ± 0,11*/†

105,7 ± 11,98*/†/#

1,99 ± 0,11*/†/#

  1. * -differences are significant vs, healthy rats, р ≤ 0,05
  2. † −differences are significant vs, AIG group, р ≤ 0,05
  3. # -differences are significant vs, Prednisolone group, p ≤ 0,05