International Journal of Phytomedicine and Phytotherapy
Table 3 Effect of therapy with prednisolone, CAN and their combination on renal function in autoimmune glomerulonephritis (mean ± SEM, n = 8 in each group)
From: Efficiency of Canephron N in complex treatment of experimental heymann glomerulonephritis
Groups of animals | Study parameters | |||||
|---|---|---|---|---|---|---|
Diuresis, mL/day | GFR, mL/min | Protein, g/mmol Cr | Erythrocytes, ×103/mL | Leukocytes, ×103/mL | Casts, units/mL | |
Healthy | 13,3 ± 0,6 | 4,50 ± 0,32 | 0,13 ± 0,01 | 1,87 ± 0,69 | 7,6 ± 1,3 | 10,0 ± 4,2 |
AIG | 5,6 ± 0,5* | 0,63 ± 0,13* | 1,05 ± 0,14* | 27,25 ± 5,47* | 324,4 ± 50,6* | 102,5 ± 25,9 * |
AIG + Prednisolone | 10,5 ± 0,9*/† | 2,98 ± 0,45*/† | 0,43 ± 0,03*/† | 9,25 ± 1,25*/† | 197,0 ± 29,.2*/† | 23,6 ± 3,2† |
AIG + CAN | 9,7 ± 0,9*/† | 1,37 ± 0,14*/†/# | 0,70 ± 0,05*/# | 15,12 ± 0,79*/# | 149,5 ± 46,6*/† | 48,2 ± 5,3*/# |
AIG + Prednisolone + CAN | 12,5 ± 1,1† | 3,24 ± 0,23*/† | 0,29 ± 0,05*/† | 5,00 ± 0,75*/†/# | 82,6 ± 7,7*/†/# | 19,0 ± 3,8† |