International Journal of Phytomedicine and Phytotherapy
Table 1 Effect of Costus afer on the average body, absolute and relative kidney weight, feed and fluid intake of CsA induced nephrotoxic rat
Treatments | Body Weight Gain(g) (initial –final BW) | Body Weight (BW)(g) | Absolute Kidney Weight (AKW)(g) | Relative Kidney Weight (%) | Feed intake (g/d) | Fluid intake (ml/d) |
|---|---|---|---|---|---|---|
NC (1 ml/kg water) | 22.00(29.02 %) | 97.80 ± 3.35 | 0.50 ± 0.08 | 0.51 ± 2.36 | 71.800 ± 9.46 | 182.80 ± 6.88 |
TC (CsA (50 mg/kg) | 1.2 (0.9 %) | 134.80 ± 3.56 | 0.70 ± 0.05 | 0.52 ±1.40 | 64.74 ± 13.24 | 152.80 ± 34.65 |
CsA+375 mg/kg CA extract | 12.00 (10.61 %) | 125.00 ± 6.33 | 0.70 ± 0.02 | 0.56 ± 0.25 | 68.00 ± 9.97 | 170.00 ±9.72 |
CsA +750 mg/kg CA extract | 14 (12.99 %) | 121.80 ± 5.81 | 0.63 ± 0.02 | 0.52± 0.38 | 60.70 ± 14.18 | 158.50 ± 22.736 |
CsA +1125 mg/kg CA extract | 13.00 (13.26 %) | 111.00 ± 10.77 | 0.60 ± 0.07 | 0.54± 0.62 | 68.15 ± 5.51 | 178.20 ±7.24 |
CsA + 100 mg/kgSilymarin | 7.0 (4.50 %) | 162.20 ± 5.07 | 0.80 ± 0.03 | 0.49± 0.611 | 54.30 ± 16.13 | 161.50 ± 24.95 |