Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 1 Effects of the medicinal plants on liver enzymes in acetaminophen-induced hepatotoxic rats

From: An invivo study on the hepato-protective effects of Crocus sativus, Ziziphus jujuba and Berberis vulgaris against acute acetaminophen and rifampicin-induced hepatotoxicity

Experimental groups ALT (U/L) AST (U/L) ALP (U/L) LDH (U/L)
Healthy Control 87 ± 12* 97 ± 9* 340 ± 37* 474 ± 29*
Healthy Control + silymarin 70 ± 8* 99 ± 13* 440 ± 45* 321 ± 27*
AIHa Control 480 ± 31 385 ± 32 745 ± 43 890 ± 47
AIH + B. vulgaris (100 mg/kg) 340 ± 21 170 ± 12* 370 ± 36* 560 ± 41*
AIH + B. vulgaris (200 mg/kg) 290 ± 14* 158 ± 11* 340 ± 32* 315 ± 19*
AIH + Z. Jujuba(100 mg/kg) 222 ± 18* 110 ± 10* 430 ± 27* 237 ± 21*
AIH + Z. Jujuba(200 mg/kg) 208 ± 21* 95 ± 12* 314 ± 39* 230 ± 24*
AIH + C. sativus (petal) (100 mg/kg) 225 ± 17* 162 ± 22* 416 ± 36* 710 ± 42*
AIH + C. sativus (petal) (200 mg/kg) 138 ± 9* 144 ± 11* 364 ± 16* 615 ± 34*
AIH + C. sativus (stigma) (40 mg/kg) 260 ± 13* 177 ± 18* 412 ± 28* 640 ± 31*
AIH + C. sativus (stigma) (80 mg/kg) 240 ± 19* 140 ± 15* 390 ± 29* 525 ± 35*
AIH + Silymarin 117 ± 12* 110 ± 17* 310 ± 21* 520 ± 37*
AIH + Mix (PS)b 119 ± 11* 105 ± 8* 320 ± 29* 510 ± 43*
AIH + Mix (ZB)b 107 ± 16* 75 ± 9* 310 ± 16* 350 ± 24*
  1. In each column, *was considered significant at P < 0.05 when compared with the AIH group
  2. aAIH: acetaminophen-induced hepatotoxic group
  3. bZB: mixture of Z.jujuba and B.vulgaris in low dose, PS: mixture of C.sativus petals and stigma in low dose