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International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of the medicinal plants on total antioxidant capacity and lipid peroxidation in acetaminophen-induced hepatotoxicity in rats

From: An invivo study on the hepato-protective effects of Crocus sativus, Ziziphus jujuba and Berberis vulgaris against acute acetaminophen and rifampicin-induced hepatotoxicity

Experimental groups Total Antioxidant Capacity (TAC) (μmol/l) Malondialdehyde (MDA) (μmol/l)
Healthy Control 760 ± 21* 1.9 ± 0.61*
Healthy Control + silymarin 756 ± 14* 2.1 ± 0.72*
AIHa Control 543 ± 16 5.4 ± 0.64
AIH + B. vulgaris (100 mg/kg) 557 ± 22 4.1 ± 0.32
AIH + B. vulgaris (200 mg/kg) 590 ± 18* 3.6 ± 0.43*
AIH + Z. jujuba (100 mg/kg) 598 ± 16 3.4 ± 0.12
AIH + Z. jujuba (200 mg/kg) 654 ± 17* 2.9 ± 0.21*
AIH + C. sativus (petal) (100 mg/kg) 560 ± 14 3.2 ± 0.19
AIH + C. sativus (petal) (200 mg/kg) 615 ± 24* 2.8 ± 0.17*
AIH + C. sativus (stigma) (40 mg/kg) 595 ± 12 3 ± 0.21
AIH + C. sativus (stigma) (80 mg/kg) 632 ± 21* 2.2 ± 0.32*
AIH + Silymarin 690 ± 17* 2.1 ± 0.19*
AIH + Mix (PS)b 682 ± 25* 2 ± 0.32*
AIH + Mix (ZB)b 695 ± 23* 2.1 ± 0.25*
  1. In each column, *was considered significant at P < 0.05 when compared with the AIH group
  2. aAIH: acetaminophen-induced hepatotoxic group
  3. bZB: mixture of Z.jujuba and B.vulgaris in low dose, PS: mixture of C.sativus petals and stigma in low dose