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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of the medicinal plants on total antioxidant capacity and lipid peroxidation in acetaminophen-induced hepatotoxicity in rats

From: An invivo study on the hepato-protective effects of Crocus sativus, Ziziphus jujuba and Berberis vulgaris against acute acetaminophen and rifampicin-induced hepatotoxicity

Experimental groups

Total Antioxidant Capacity (TAC) (μmol/l)

Malondialdehyde (MDA) (μmol/l)

Healthy Control

760 ± 21*

1.9 ± 0.61*

Healthy Control + silymarin

756 ± 14*

2.1 ± 0.72*

AIHa Control

543 ± 16

5.4 ± 0.64

AIH + B. vulgaris (100 mg/kg)

557 ± 22

4.1 ± 0.32

AIH + B. vulgaris (200 mg/kg)

590 ± 18*

3.6 ± 0.43*

AIH + Z. jujuba (100 mg/kg)

598 ± 16

3.4 ± 0.12

AIH + Z. jujuba (200 mg/kg)

654 ± 17*

2.9 ± 0.21*

AIH + C. sativus (petal) (100 mg/kg)

560 ± 14

3.2 ± 0.19

AIH + C. sativus (petal) (200 mg/kg)

615 ± 24*

2.8 ± 0.17*

AIH + C. sativus (stigma) (40 mg/kg)

595 ± 12

3 ± 0.21

AIH + C. sativus (stigma) (80 mg/kg)

632 ± 21*

2.2 ± 0.32*

AIH + Silymarin

690 ± 17*

2.1 ± 0.19*

AIH + Mix (PS)b

682 ± 25*

2 ± 0.32*

AIH + Mix (ZB)b

695 ± 23*

2.1 ± 0.25*

  1. In each column, *was considered significant at P < 0.05 when compared with the AIH group
  2. aAIH: acetaminophen-induced hepatotoxic group
  3. bZB: mixture of Z.jujuba and B.vulgaris in low dose, PS: mixture of C.sativus petals and stigma in low dose
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