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International Journal of Phytomedicine and Phytotherapy

Table 3 Analgesic activity of MEIL by hot plate method

From: Evaluation of pharmacological activities of methanol extract of Ixora cuneifolia leaves

Group

Reaction time at different time intervals (in seconds)

0 Hour

1st Hour

2nd Hour

3rd Hour

4th Hour

Control

10.70 ± 1.893

8.00 ± 1.820

6.58 ± 1.432

5.52 ± 1.227

5.00 ± 0.989

Standard (Tramadol)

9.14 ± 1.171

12.60 ± 2.113** (37.85)

14.16 ± 2.406*** (54.92)

15.96 ± 1.512*** (74.61)

12.48 ± 1.561*** (36.54)

MEIL (250 mg/kg)

9.08 ± 0.535

12.18 ± 0.570** (33.36)

13.64 ± 0.404*** (50.20)

14.14 ± 0.583*** (55.73)

12.34 ± 0.282*** (35.90)

MEIL (500 mg/kg)

8.54 ± 0.587

10.96 ± 0.758* (28.34)

12.88 ± 0.505*** (50.80)

14.76 ± 0.592*** (72.81)

11.76 ± 0.704*** (37.89)

  1. MEIL: Methanol Extract of Ixora cuneifolia leaf, Values in the table are expressed as mean ± SEM, (n = 5). Values in parenthesis indicates percentage inhibition *P < 0.05, **P < 0.01, ***P < 0.001 were considered statistically significant in comparison with control