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International Journal of Phytomedicine and Phytotherapy

Table 4 The effect of MEPH on rota-rod test in mice

From: Evaluation of sedative and anxiolytic activities of methanol extract of leaves of Persicaria hydropiper in mice

Treatment

Dose (mg/kg)

Performance time (s)

Number of falls

Control

0.1 ml/mouse

176.00 ± 1.89

1.40 ± 0.74

Diazepam

1

152.00 ± 1.54***

14.60 ± 0.40***

MEPH

50

174.40 ± 1.72

2.00 ± 0.89

MEPH

200

137.00 ± 1.22***

15.20 ± 0.73***

MEPH

350

138.60 ± 1.07***

13.80 ± 0.73***

MEPH

500

116.40 ± 1.28***

17.00 ± 0.63***

  1. Each value is presented as the mean ± SEM (n = 10), MEPH = Methanol extract of Persicaria hydropiper leaves. “***p < 0.001, **p < 0.01, *p < 0.05 vs control group (Dunnett’s test)”