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International Journal of Phytomedicine and Phytotherapy

Table 4 The effect of MEPH on rota-rod test in mice

From: Evaluation of sedative and anxiolytic activities of methanol extract of leaves of Persicaria hydropiper in mice

Treatment Dose (mg/kg) Performance time (s) Number of falls
Control 0.1 ml/mouse 176.00 ± 1.89 1.40 ± 0.74
Diazepam 1 152.00 ± 1.54*** 14.60 ± 0.40***
MEPH 50 174.40 ± 1.72 2.00 ± 0.89
MEPH 200 137.00 ± 1.22*** 15.20 ± 0.73***
MEPH 350 138.60 ± 1.07*** 13.80 ± 0.73***
MEPH 500 116.40 ± 1.28*** 17.00 ± 0.63***
  1. Each value is presented as the mean ± SEM (n = 10), MEPH = Methanol extract of Persicaria hydropiper leaves. “***p < 0.001, **p < 0.01, *p < 0.05 vs control group (Dunnett’s test)”