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International Journal of Phytomedicine and Phytotherapy

Table 7 The effect of MEPH on light-dark box test in mice

From: Evaluation of sedative and anxiolytic activities of methanol extract of leaves of Persicaria hydropiper in mice

Treatment

Dose (mg/kg)

Latency time (s)

Transition

Time spent in the light compartment(s)

Time spent in the dark compartment(s)

Control

0.1 ml/mouse

31.00 ± 0.83

20.40 ± 0.67

248.80 ± 1.71

51.20 ± 2.43

Diazepam

1

10.00 ± 0.31***

7.00 ± 0.44***

92.60 ± 1.43***

207.40 ± 1.43***

MEPH

50

28.20 ± 0.37

19.40 ± 0.40

226.80 ± 1.82***

72.20 ± 1.15***

MEPH

200

26.00 ± 0.31***

16.40 ± 0.67***

225.00 ± 1.58***

105.00 ± 1.58***

MEPH

350

21.00 ± 0.31***

11.40 ± 0.98***

149.20 ± 1.80***

105.60 ± 1.16***

MEPH

500

13.80 ± 0.73***

9.80 ± 0.37***

101.80 ± 1.39***

198.20 ± 1.39***

  1. Each value is presented as the mean ± SEM (n = 10), MEPH = Methanol extract of Persicaria hydropiper leaves. “***p < 0.001, **p < 0.01, *p < 0.05 vs control group (Dunnett’s test)”