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International Journal of Phytomedicine and Phytotherapy

Table 1 Results of the anti-inflammatory activity of the total ethanolic extract and different fractions of A. hirtum leave using carrageenan – induced paw edema method

From: Anti-inflammatory, analgesic, antipyretic and antidiabetic activities of Abutilon hirtum (Lam.) Sweet

Group Thickness of the paw (mm)
0 h 30 min 1 h 2 h 3 h 4 h 5 h
Control (−ve) 7.37 ± 0. 12 7.37 ± 0.12 7.5 ± 0.0 7.62 ± 0.12 7.62 ± 0.12 7.87 ± 0.23 7.87 ± 0.23
Total extract (300 mg/kg) 7.25 ± 0.14 6.87 ± 0. 12 6.25 ± 0.14*** 5.62 ± 0.23*** 4.62 ± 0.23*** 4.0 ± 0.20*** 3.87 ± 0.12***
Petroleum ether fraction (300 mg/kg) 7.25 ± 0.14 7.12 ± 0.12 6.75 ± 0.14* 6.37 ± 0.23** 5.75 ± 0.32*** 5.25 ± 0.25*** 4.87 ± 0.12***
Chloroform fraction (300 mg/kg) 7.25 ± 0.14 6.62 ± 0.23* 6.37 ± 0.23*** 5.62 ± 0.23*** 4.87 ± 0.31*** 4.0 ± 0.2*** 3.87 ± 0.12***
Ethyl acetate fraction (300 mg/kg) 7.25 ± 0.14 7.0 ± 0.0 6.75 ± 0.14* 6.5 ± 0.2** 5.87 ± 0.12*** 5.37 ± 0.37*** 5.37 ± 0.37***
Aqueous fraction (300 mg/kg) 7.12 ± 0. 12 7.12 ± 0.12 6.75 ± 0.14* 6.5 ± 0.2** 6.0 ± 0.20*** 4.87 ± 0.12*** 4.75 ± 0.14***
Indomethacin (8 mg/kg) 7.25 ± 0.14 6.5 ± 0.2** 6.0 ± 0.20*** 5.62 ± 0.23*** 5.37 ± 0.23*** 4.12 ± 0.12*** 3.75 ± 0.14***
  1. The results are presented as the mean ± S.E.M Standard error of the mean. Differences with respect to the control group were calculated using the student’s T-test (*P < 0.05, **P < 0.01, ***P < 0.001)