Table 5 Results of the antipyretic activity of the total ethanolic extract and different fractions of A. hirtum leaves on yeast–induced pyrexia method

Control (−ve)

38.73 ± 0.08

38.85 ± 0.02

38.85 ± 0.05

38.88 ± 0.02

39.55 ± 0.13

39.9 ± 0.04

39.98 ± 0.08***

Total extract (300 mg/kg)

38.63 ± 0.10

38.2 ± 0.07***

37.3 ± 0.09***

36.35 ± 0.06 ***

36.23 ± 0.04***

36.13 ± 0.04***

36.05 ± 0.02***

Petroleum ether fraction (300 mg/kg)

38.68 ± 0.08

38.23 ± 0.12***

38.15 ± 0.02***

37.33 ± 0.10***

37.4 ± 0.17***

37.13 ± 0.07***

37.1 ± 0.04***

Chloroform fraction (300 mg/kg)

38.7 ± 0.09

38.73 ± 0.04

38.63 ± 0.04

38.5 ± 0.04***

38.43 ± 0.04***

38.48 ± 0.04***

38.5 ± 0.04***

Ethyl acetate fraction (300 mg/kg)

38.75 ± 0.09

38.5 ± 0.04*

38.2 ± 0.07***

37.63 ± 0.06***

37.55 ± 0.06***

37.2 ± 0.04***

37.05 ± 0.02***

Aqueous fraction (300 mg/kg)

38.73 ± 0.06

38.43 ± 0.08**

38 ± 0.13***

37.48 ± 0.02***

37.43 ± 0.04***

37.25 ± 0.11***

37.13 ± 0.07***

Acetylsalicylic acid (100 mg/kg)

38.78 ± 0.07

38.48 ± 0.06**

37.7 ± 0.16***

37.43 ± 0.04***

37.2 ± 0.04***

37.2 ± 0.07***

37.15 ± 0.02***