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International Journal of Phytomedicine and Phytotherapy

Table 8 Effects of methanol extract of Zingiber officinale on serum biochemical parameters and body weight gain in rats

From: In-vitro antioxidants, antimicrobial and toxicological evaluation of Nigerian Zingiber officinale

  Extract concentration (mg/kg bwt)  
  75 150 300 600 Control
Protein (mg/dl) 39.42 ± 2.34a 41.23 ± 3.45a 40.18 ± 3.41a 39.58 ± 3.66a 37.57 ± 2.78a
Bilirubin (mg/dl) 4.53 ± 0.34a 5.32 ± 0.78a 5.04 ± 0.21a 7.70 ± 0.45b 5.32 ± 0.46a
Albumin (mg/dl) 3.76 ± 0.78a 3.97 ± 0.56a 3.91 ± 0.06a 3.47 ± 0.24a 3.43 ± 0.36a
ALT(U/L) 5.43 ± 0.56a 5.65 ± 0.45a 5.10 ± 0.34a 5.40 ± 0.44a 5.45 ± 0.24a
AST(U/L) 25.45 ± 2.45a 28.05 ± 1.56a 25.70 ± 1.34a 28.33 ± 1.45a 28.30 ± 2.35a
ALP (U/L) 142.34 ± 5.67a 138.45 ± 2.56a 145.03 ± 2.56a 139.75 ± 4.56a 141.35 ± 3.56a
Creatinine 10.68 ± 1.23a 10.42 ± 0.45a 11.6 ± 0.95a 14.21 ± 0.34b 11.34 ± 0.45a
Urea 27.54 ± 4.56a 30.45 ± 1.23ab 26.73 ± 2.67a 37.32 ± 3.45b 26.78 ± 2.46a
Chloride 367.45 ± 9.87b 395.56 ± 8.67b 398.54 ± 11.56b 238.70 ± 7.81a 378.0 ± 9.87b
Potassium 5.32 ± 0.68a 5.65 ± 0.34a 7.76 ± 1.02b 5.28 ± 0.45a 5.54 ± 0.45a
Sodium 22.56 ± 3.46a 27.84 ± 3.67a 23.33 ± 3.56a 25.6 ± 2.86a 24.56 ± 1.35a
Initial Body weight (g) 128.45 ± 3.69b 137.78 ± 5.75b 138.15 ± 2.17a 115.50 ± 2.35a 125.67 ± 2.34a
Final Body weight (g) 158.23 ± 3.67b 169.45 ± 4.92b 166.58 ± 2.15b 137.35 ± 1.57b 154.92 ± 2.79b
Weight gain (g) 29.78 31.67 28.34 21.85 29.25
  1. Values are mean ± SEM of 5 determinations. Values along the same row with same superscripts alphabets are not significantly different (p < 0.05)