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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of Citrus macroptera peel powder supplementation on biochemical parameters in plasma and liver of CCl4 treated rats

From: Caffeic acid rich Citrus macroptera peel powder supplementation prevented oxidative stress, fibrosis and hepatic damage in CCl4 treated rats

Parameters Groups
Control Control+Citrus macroptera CCl4 CCl4 + Citrus macroptera
Plasma
 AST(U/L) 34.45 ± 3.85 35.89 ± 3.46 ns 65.46 ± 8.87a 47.37 ± 4.85b
 ALT(U/L) 30.15 ± 2.94 31.58 ± 2.87 ns 66.04 ± 2.87a 43.07 ± 5.88b
 ALP(U/L) 57.60 ± 1.38 33.76 ± 4.95b 80.35 ± 5.58a 37.57 ± 7.21b
 MDA(nmol/mL) 7.27 ± 0.19 11.01 ± 0.47 ns 17.27 ± 1.79a 9.81 ± 0.42b
 NO (nmol/mL) 3.87 ± 0.27 4.43 ± 0.70 ns 6.80 ± 0.65a 3.42 ± 0.61b
 APOP (nmol/mL equivalent to Chloramine-T) 228.33 ± 10.66 326.35 ± 56.23 ns 736.27 ± 54.83a 347.38 ± 26.18b
 GSH (ng/mg protein) 11.85 ± 0.51 11.25 ± 0.74 ns 7.50 ± 0.40a 13.63 ± 1.22b
 Catalase (U/min) 7.17 ± 0.79 10.50 ± 1.20 ns 5.33 ± 1.05 ns 7.00 ± 1.06 ns
Liver
 NO (nmol/mL) 14.12 ± 0.91 12.35 ± 0.92 ns 15.87 ± 2.23 ns 12.47 ± 1.20 ns
 MDA (nmol/mL) 38.77 ± 1.84 40.31 ± 2.02 ns 64.41 ± 4.89ba 51.33 ± 5.13 ns
 APOP (nmol/mL equivalent to Chloramine-T) 632.06 ± 33.84 497.78 ± 29.20 ns 968.57 ± 70.27a 566.43 ± 48.60b
 Catalase (U/min) 20.83 ± 3.52 24.17 ± 3.00 ns 14.17 ± 2.01a 23.33 ± 2.47b
  1. Values are presented as mean ± SEM. N = 6 in each group or otherwise specified. One way ANOVA with Bonferroni tests were done as post hoc test. Values are considered significant at p < 0.05. Values are considered significance at p < 0.05. control vs CCl4 significanltly different a < 0.05. CCl4 vs Citrus macroptera treatment which are significantly different at b < 0.05. ns- non significant. APOP-Advanced protein oxidation product expressed as nmol/mL equivalent to Chloramine-T