International Journal of Phytomedicine and Phytotherapy
Table 3 Antiangiogenic effect of S. ochocao and Sorafenib
Drugs | Dose μg/mL per œuf | Tested eggs (n) | Embryos status after 48 h | Branches vessels nombers | %AIA | IC50 (μg/mL) | P value |
|---|---|---|---|---|---|---|---|
PBS (negative control) | – | 5 | living | 15 ± 0.954 | – | – | 0.002 |
Sorafenib (positive control) | 62.5 | 5 | living | 6 ± 0.753 | 60 ± 1.056 | 0.197 ± 0.062 | |
125 | 5 | living | 2 ± 0.954 | 86.667 ± 1.045 | |||
250 | 5 | living | 1 ± 0.976 | 93.333 ± 0.965 | |||
500 | 5 | living | 0 | 100 | |||
Water extract of S. ochocao | 62.5 | 5 | living | 8 ± 0.834 | 26.667 ± 1.634 | 1.153 ± 0.089 | |
125 | 5 | living | 5 ± 0.850 | 60 ± 0.507 | |||
250 | 5 | living | 3 ± 0.500 | 73.333 ± 0.910 | |||
500 | 5 | living | 0 | 100 |