Phytochemical studies, antiangiogenic, anti-inflammatory and antioxidant activities of Scyphocephalium ochocoa Warb. (Myristicaceae), medicinal plant from Gabon

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of S. ochocoa extracts and diclofenac sodium against protein denaturation

% Inhibition of S. ochocoa extracts				Sodium diclofenac
Conc. (μg/mL)	Water	Water-Ethanol	Ethanol	Conc. (μg/mL)	% Inhibition
100	66.332 ± 1.777	65.201 ± 1.178	56.281 ± 1.264	500	129.481 ± 1.508
50	31.281 ± 1.244	46.357 ± 1.599	39.573 ± 1.954	250	103.015 ± 2.970
25	17.714 ± 1.178	38.317 ± 1.797	32.161 ± 2.132	125	96.566 ± 2.609
12.5	13.693 ± 1.178	33.040 ± 2.442	24.497 ± 2.152	62.5	71.106 ± 3.048
6.25	4.899 ± 1.533	17.588 ± 1.553	10.678 ± 1.244	31.25	43.300 ± 1.002
IC₅₀ (μg/mL)	74.577 ± 3.456	34.775 ± 2.543	40.345 ± 3.567		35.746 ± 2.374
P value	0.014	0.582

There is no significant difference between the IC₅₀ of the water-ethanol, ethanol extract and diclofenac (p value = 0.582). On the other hand the difference is made with the water extract (p value = 0.014)