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International Journal of Phytomedicine and Phytotherapy

Table 1 Summary of biochemical parameters for all treatment groups

From: Pharmacological influences of natural products as bioenhancers of silymarin against carbon tetrachloride-induced hepatotoxicity in rats

Parameters

Group A

Group B

Group C

Group D

Group E

Group F

Group G

Group H

 

Normal control

Toxic control

Plain Sily tab

Sily + Lys (10%) tab

Sily + Pip (10%) tab

Sily + FA (1:1) tab

Sily + FA (1:1) + Pip (10%) tab

Marketed Tab

SGOT (IU/L)

67.25 ± 4.29

303.3 ± 1.85a

225.3 ± 6.02b

175.2 ± 4.55b

125.4 ± 5.58b

106.2 ± 3.89b

83.03 ± 2.08b

199.2 ± 8.62b

SGPT (IU/L)

55.34 ± 4.27

195.6 ± 2.87a

123.5 ± 6.92b

99.14 ± 6.58b

82.89 ± 1.88b

78.90 ± 4.26 b

66.82 ± 3.14b

107.2 ± 6.56 b

ALKP (IU/L)

85.08 ± 5.17

353.3 ± 8.91a

183.5 ± 5.14b

163.8 ± 3.59b

145.0 ± 4.04b

133.3 ± 3.69b

109.8 ± 4.76b

172.2 ± 2.53b

Total Bilirubin (mg/100 mL)

0.38 ± 0.02

1.18 ± 0.04a

0.65 ± 0.03b

0.60 ± 0.01b

0.57 ± 0.02b

0.53 ± 0.03b

0.43 ± 0.04b

0.65 ± 0.03b

Total protein (g/dL)

7.37 ± 0.16

5.06 ± 0.33a

8.74 ± 0.05b

8.06 ± 0.11b

7.93 ± 0.13b

7.70 ± 0.13b

7.45 ± 0.33b

8.66 ± 0.08b

  1. Dunnett’s Multiple Comparison Tests showed that all values of group A, C, D, E, F, G, H exhibited significant changes when compared to toxic control with 99.9% CI of difference. For each group n = 5, the values are expressed as mean ± SEM. ‘a’ exhibits significant (p < 0.05) changes from normal control, whereas, ‘b’ exhibits significant (p < 0.05) change when compared to toxic control