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International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of the extract of ZBRB on castor oil induced diarrhoea in mice

From: Bioactivity studies on Zanthoxylum budrunga wall (Rutaceae) root bark

Treatment (n = 6) Dose (mg/kg) Onset of diarrhoea (min) No. of stools after 4 h % Inhibition of defecation
Control 34.00 ± 3.15* 23.00 ± 1.58*
Loperamide 3 198.60 ± 2.34* 2.40 ± 0.51* 89.56
Extract 250 101.40 ± 3.39* 7.80 ± 0.37* 66.56
  500 179.40 ± 4.83* 3.80 ± 0.49* 83.39
  1. Results are expressed as mean ± SEM, SEM Standard error for mean, n = 6 (number of mice), *P < 0.001 vs. control (Student’s t-test)