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International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of the extract of ZBRB on castor oil induced diarrhoea in mice

From: Bioactivity studies on Zanthoxylum budrunga wall (Rutaceae) root bark

Treatment (n = 6)

Dose (mg/kg)

Onset of diarrhoea (min)

No. of stools after 4 h

% Inhibition of defecation

Control

–

34.00 ± 3.15*

23.00 ± 1.58*

–

Loperamide

3

198.60 ± 2.34*

2.40 ± 0.51*

89.56

Extract

250

101.40 ± 3.39*

7.80 ± 0.37*

66.56

 

500

179.40 ± 4.83*

3.80 ± 0.49*

83.39

  1. Results are expressed as mean ± SEM, SEM Standard error for mean, n = 6 (number of mice), *P < 0.001 vs. control (Student’s t-test)