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International Journal of Phytomedicine and Phytotherapy

Fig. 6 | Clinical Phytoscience

Fig. 6

From: Hepatoprotective potentials of methanol extract of T. conophorum seeds of carbon tetrachloride induced liver damage in Wistar rats

Fig. 6

Effect of methanol extract of T. conophorum seeds on Gamma gtutamyl transferase activities in CCl4 induced hepatotoxicity in rats after 48 h of intoxication. Values are Mean ± SEM, n = 5 rats in each group. p < 0.05, a as compared with the normal control group; b as compared with the CCl4 only (group IIB). γ-GT – Gamma gtutamyl transferase CCl4- Carbon tetrachloride. Group IB (control) received distilled water and olive oil (i.p), group IIB rats were intoxicated with CCl4 in olive oil (600 mg/kg, i.p.) only on the 8th day, while groups IIIB, IVB and VB were given 100 mg/kg of silymarin, 250 mg/kg and 500 mg/kg of methanol extract, respectively for 7 days, thereafter intoxicated with CCl4 on the 8th day. Groups VIB and VIIB were intoxicated with CCl4 on the 8th day and administered 250 mg/kg and 500 mg/kg of methanol extract of T. conophorum seeds at 1 h, 6 h, 12 h, 18 h and 24 h. Fasting blood samples were collected after the last administration of the extract at 48 h of intoxication with CCl4

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