A non-interventional, prospective, multicenter study for evaluation of the use of the herbal medicinal product Canephron® N in the pediatric outpatient population in Russia

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 4 Indication groups

MedDRA System Organ Class	Indication Group	MedDRA Lowest Level Term
Infections and infestations	Urinary tract infections	Urinary tract infection
	Pyelonephritis	Pyelonephritis
		Pyelonephritis acute
		Pyelonephritis chronic
	Cystitis	Cystitis
		Cystitis hemorrhagic
Renal and urinary disorders	Dysmetabolic nephropathy / crystalluria	Crystalluria
		Hypercalciuria
		Hyperoxaluria
		Hyperphosphaturia
		Hyperuricosuria
	Urolithiasis	Calculus urinary
		Nephrolithiasis
	Nephritis	Glomerulonephritis
		Glomerulonephritis acute
		Glomerulonephritis chronic
		Nephritis
		Tubulointerstitial nephritis

Lowest Level Term (LLT) selection for different types of dysmetabolic nephropathy (including the terms: dysmetabolic nephropathy, metabolic nephropathy, crystalluria) was performed according to Project specific coding guidelines:
1) calcium type - LLT “Hypercalciuria”
2) oxalate type - LLT “Hyperoxaluria”
3) oxalate-calcium type: 1. LLT “Hyperoxaluria”; 2. LLT “Hypercalciuria”
4) urate type - LLT “Hyperuricosuria”
5) phosphate type - LLT “Hyperphosphaturia”
6) unknown type - LLT “Crystalluria”