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International Journal of Phytomedicine and Phytotherapy

Clinical Phytoscience Cover Image
Fig. 1 | Clinical Phytoscience

Fig. 1

From: Solanum nigrum confers protection against CCl4-induced experimental hepatotoxicity by increasing hepatic protein synthesis and regulation of energy metabolism

Fig. 1

Light micrographs (H & E stained) of liver (a) vehicle control mice showing normal architecture with radially arranged central vein (200 x) (b) S. nigrum control mice showing normal structure and absence of vacuolization and fatty degenerative changes (200x) (c) CCl4-treated indicating extensive cytoplasmic vacuolization and fatty infiltration (200x) (d) S. nigrum 100 mg/kg bwt plus CCl4-treated mice showing moderate necrotic changes and fatty degenerative changes and ballooning of hepatocytes (e) S. nigrum 200 mg/kg bwt plus CCl4-treated mice showing mild centrilobular necrosis degenerative changes (200x) (f) S. nigrum 300 mg/kg bwt plus CCl4-treated mice showing normal arrangement of hepatocytes and almost similar to vehicle control mice (400 x)

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