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International Journal of Phytomedicine and Phytotherapy

Clinical Phytoscience Cover Image

Table 1 Effect of S. nigrum on CCl4 -induced changes in body weight (gm) of mice

From: Solanum nigrum confers protection against CCl4-induced experimental hepatotoxicity by increasing hepatic protein synthesis and regulation of energy metabolism

Experimental groups Days of treatment
0 30
Control
 1. Untreated 32.87 ± 1.65 34.99 ± 1.67
 2. Olive oil 32.04 ± 0.15 34.74 ± 0.94
 3. S. nigrum (SN) 32.49 ± 0.94 34.93 ± 1.32
Carbon Tetrachloride (CCl4) -Treated
 4. CCl4 32.52 ± 1.23a* 27.43 ± 1.59a*
CCl4 + Solanum Nigrum (SN) Extract-Treated
 5. CCl4 + SN100 33.03 ± 1.32 b* 30.11 ± 0.99b*
 6. CCl4 + SN200 32.66 ± 1.12 b* 31.13 ± 0.45b*
 7. CCl4 + SN300 33.04 ± 0.98 b* 33.82 ± 0.53b*
  1. Results are expressed as mean ± SEM; n = 10
  2. No significant difference was noted between groups 1–3
  3. aas compared between vehicle control (group 2) and toxin-treated (group 4),
  4. bas compared between toxin-treated (group 4) and toxin + antidote-treated (groups 5–7)
  5. Level of significance *p < 0.001