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International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of MESI in OFT

From: Evaluation of the antidepressant-like activity of the methanolic extract of the seeds of Sesamum indicum

Treatment Doses Locomotion Rearing Defecation
Deionized water 01 ml/mice 98.4 ± 7.07 25.4 ± 1.435 1.2 ± 0.2
Imipramine Hydrochloride 30 mg/kg 208.6 ± 13.58* 35.8 ± 1.428* 3.4 ± 0.4*
MESI 50 mg/kg 129.75 ± 5.12* 27.75 ± 0.854 1.75 ± 0.25
MESI 100 mg/kg 137.2 ± 9.015* 30.8 ± 1.356* 2.8 ± 0.49*
MESI 200 mg/kg 167.4 ± 5.38* 34.2 ± 1.281* 3.4 ± 0.245*
  1. Values are presented as mean ± SEM (n = 5)
  2. P* < 0.05 compared with the control group (Dunnett’s test)