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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of MESI in OFT

From: Evaluation of the antidepressant-like activity of the methanolic extract of the seeds of Sesamum indicum

Treatment

Doses

Locomotion

Rearing

Defecation

Deionized water

01 ml/mice

98.4 ± 7.07

25.4 ± 1.435

1.2 ± 0.2

Imipramine Hydrochloride

30 mg/kg

208.6 ± 13.58*

35.8 ± 1.428*

3.4 ± 0.4*

MESI

50 mg/kg

129.75 ± 5.12*

27.75 ± 0.854

1.75 ± 0.25

MESI

100 mg/kg

137.2 ± 9.015*

30.8 ± 1.356*

2.8 ± 0.49*

MESI

200 mg/kg

167.4 ± 5.38*

34.2 ± 1.281*

3.4 ± 0.245*

  1. Values are presented as mean ± SEM (n = 5)
  2. P* < 0.05 compared with the control group (Dunnett’s test)
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