Table 2 CNS depressant activity test result of C. turgida extracts by hole cross method
From: Neuropharmacological potential of Ceriscoides turgida (Roxb.) leaf and root in mice
Group | Dose (mg/kg) | Number of movement (% of movements Inhibition) | ||||
|---|---|---|---|---|---|---|
0 min | 30 min | 60 min | 90 min | 120 min | ||
Control | 10 ml/kg | 7.8 ± 1.24 | 10 ± 0.95 | 11.2 ± 1.24 | 10 ± 1.30 | 10 ± 0.51 |
Standard | 1 | 7.8 ± 0.58 | 5.2 ± 0.58 (48%) | 3.4 ± 0.51 (69.6%) | 2.2 ± 0.58 (78%) | 0.8 ± 0.37 (92%) |
Leaf extract | 100 | 8.2 ± 0.58 | 5.4 ± 0.51 (46%) | 4.2 ± 0.37 (62.5%) | 3.8 ± 0.37* (62%) | 2.8 ± 0.37* (72%) |
Leaf extract | 200 | 8.2 ± 0.86 | 5.6 ± 0.51 (44%) | 4.2 ± 0.66* (62.5%) | 3.2 ± 0.49* (68%) | 2.6 ± 0.24* (74%) |
Root extract | 100 | 7 ± 0.71 | 5.2 ± 0.58 (48%) | 3.8 ± 0.58* (66%) | 3.6 ± 0.51 (64%) | 2.2 ± 0.37* (72%) |
Root extract | 200 | 8.2 ± 0.97 | 5.4 ± 0.81 (46%) | 3.8 ± 0.66* (66%) | 2.6 ± 0.68* (74%) | 1.4 ± 0.51* (86%) |