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International Journal of Phytomedicine and Phytotherapy

Table 4 Data of CNS depressant activity test of C. turgida extracts by open field method

From: Neuropharmacological potential of Ceriscoides turgida (Roxb.) leaf and root in mice

Group

Dose (mg/kg)

Number of movement (% of Inhibition)

0 min

30 min

60 min

90 min

120 min

Control

10 ml/kg

61 ± 4.32

60.2 ± 4.41

66.6 ± 5.88

60.2 ± 6.06

51.2 ± 3.46

Standard

1

55.8 ± 5.17

21 ± 1.87 (74.1%)

15.6 ± 1.67 (76.6%)

11.2 ± 1.46 (81.4%)

7.4 ± 0.51 (85.5%)

Leave extract

100

54 ± 6.47

38 ± 3.49 (36.4%)

32 ± 1.73 (51.9%)

23.4 ± 1.29 (61.1%)

16.2 ± 0.86* (68.4%)

Leave extract

200

52.8 ± 3.43

33.4 ± 4.48 (44.5%)

22.4 ± 3.36 (66.4%)

13 ± 1.41* (78.7%)

8.2 ± 1.16* (84%)

Root extract

100

57.8 ± 2.99

35.6 ± 5.06 (40.9%)

24.6 ± 2.99 (63.1%)

15.2 ± 1.39* (74.8%)

9 ± 0.95* (82.4%)

Root extract

200

58.2 ± 2.85

29.2 ± 2.82 (51.5%)

15.8 ± 1.02* (76.2%)

9.4 ± 1.60* (84.4%)

6.2 ± 0.97* (87.9%)

  1. Values are presented as Mean ± SEM (n = 5), P < 0.05, which is significant compared with the control group (two-way ANOVA followed by Bonferroni’s test)
  2. *Indicates the significance of the result