Table 2 The effects of oral administration of extracts (aqueous or ethanol) of A. wilkesiana leaves on serum bicarbonate, urea and creatinine concentrations of salt-loaded rabbits

SERUM

DAY

1 (Cont. Salt)

2 (Salt+ Aq. Ext)

3 (Salt +Et. Ext)

4 (Salt+DW)

5 (Control)

 BICARBONATE (mmol/l)

71

28.16 ± 5.81^ax

30.79 ± 2.09^ax

37.37 ± 1.05^ax

34.74 ± 2.73^ax

59.74 ± 3.10^bx

78

42.10 ± 1.60^{dy 33% increase}

11.31 ± 0.53^{cy 63% decrease}

14.21 ± 2.41^{cy 62% decrease}

15.79 ± 1.64^{cy 55% decrease}

29.74 ± 3.73^{ey 50% decrease}

 UREA (mg/dl)

71

37.08 ± 2.59^ax

35.52 ± 1.74^ax

32.38 ± 1.60^ax

29.84 ± 1.38^ax

34.86 ± 3.43^ax

78

33.38 ± 4.34^bx

35.32 ± 0.28^bx

46.42 ± 0.61^cy

33.97 ± 1.69^bx

37.65 ± 2.86^bx

 CREATININE (mg/dl)

71

0.86 ± 0.13^ax

0.88 ± 0.04^ax

0.97 ± 0.16^ax

1.17 ± 0.06^ax

1.01 ± 0.02^ax

78

0.81 ± 0.06^bx

0.76 ± 0.04^bx

0.83 ± 0.06^bx

0.93 ± 0.06^bx

0.85 ± 0.09^bx