Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 4 Effects of administration of ethanolic extract, aqueous and n-hexane partitioned extracts of X. aethiopica (Dunal) A. Rich on the antioxidant system in the spleen of healthy rats

From: Influence of ethanolic extracts of dried fruit of Xylopia aethiopica (Dunal) A. Rich on haematological and biochemical parameters in healthy Wistar rats

Group

GSH (μmol/g protein)

MDA (μmol/mg of tissue)

Total Thiol (μmol/g of protein)

CAT (U/g of protein)

SOD (U/g of protein)

POD (U/g of protein)

γ-GT (U/g of protein)

Control

0.38 ± 0.10a

84.81 ± 4.89a

3.26 ± 0.48a

38.73 ± 16.21a

1.39 ± 0.29a

1.26 ± 0.34a

0.02 ± 0.031a

HPE 100 mg/kg

1.24 ± 0.04b

84.81 ± 0.93a

2.53 ± 0.07b

26.26 ± 5.59a

0.98 ± 0.03a

1.06 ± 0.33a

0.02 ± 0.004a

HPE 200 mg/kg

0.62 ± 0.17a

68.46 ± 10.05b

2.08 ± 0.06b

31.59 ± 1.55a

1.08 ± 0.17a

1.20 ± 0.18a

0.01 ± 0.002a

APE 100 mg/kg

0.26 ± 0.02a

86.35 ± 1.34a

2.80 ± 0.14ab

41.20 ± 5.56ab

1.30 ± 0.26a

1.66 ± 0.62a

0.01 ± 0.002a

APE 200 mg/kg

1.53 ± 0.11b

85.38 ± 8.27a

2.90 ± 0.20ab

35.65 ± 6.56a

1.13 ± 0.10a

0.79 ± 0.07a

0.01 ± 0.001a

ECE 100 mg/kg

1.25 ± 0.27b

94.23 ± 4.14c

3.19 ± 0.45a

40.03 ± 6.63ab

1.18 ± 0.21a

1.21 ± 0.21a

0.01 ± 0.001a

ECE 200 mg/kg

1.2 ± 0.08b

93.27 ± 10.38ac

1.84 ± 0.29c

62.11 ± 11.44b

0.88 ± 0.12a

0.93 ± 0.14a

0.01 ± 0.003a

  1. Data presented as Mean ± SEM, n = 5, values within a column with different superscript are significantly different at p < 0.05. HPE n-hexane partitioned extract, APE Aqueous partitioned extract, ECE Ethanolic extract, GSH Reduced Glutathione, MDA malondialdehyde, CAT Catalase, SOD Superoxide dismutase, POD Peroxidase, γ-GT γ-glutamyl transpeptidase