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International Journal of Phytomedicine and Phytotherapy

Table 1 Effect of Crude Sulphated Polysaccharides of Sargassum swartzii on Liver Enzymes and Bilirubin in Acetaminophen-Intoxicated Rats

From: Protective effect of crude sulphated polysaccharides from Sargassum Swartzii (Turn.) C.Ag. against acetaminophen induced liver toxicity in rats

Groups

ALT (U/L)

AST (U/L)

ALP (U/L)

LDH (U/L)

Bilirubin (mg/dl)

Normal control

27d ± 1.7

88d ± 8

45c ± 6.2

238.6d ± 10.2

0.56c ± 0.051

Acetaminophen (AAP) control

64a ± 7.8

187.6a ± 9.29

124a ± 4.3

542.6a ± 17.6

0.93a ± 0.054

Silymarin (35 mg/kg) + AAP

37.3bc ± 4.5

139bc ± 8.88

68.3b ± 7.5

375b ± 17.5

0.76b ± 0.056

S. swartzii EW1 + AAP

33.3cd ± 2.5

121c ± 12.5

47.6c ± 1.5

318c ± 10.5

0.76b ± 0.06

S. swartzii EW2 + AAP

45b ± 4

154b ± 14

60.3b ± 0.57

375b ± 17.5

0.73b ± 0.052

  1. The values are expressed as means ± Standard error (n = 6 animals per group)
  2. The values having the same superscript within the column are not significantly (p < 0.05) different according to Duncan’s multiple range test