Anti-inflammatory, antinociceptive and antidiarrhoeal activities of methanol and ethyl acetate extract of Hemigraphis alternata leaves in mice

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of standard and MHAL and EAHAL on cotton pellet induced granuloma formation test

Treatment groups	Dose	Granuloma weight (mg)	% of inhibition	p value
Control	10 mL/kg	31.60 ± 1.91	0.00 ± 0.00	–
DS	100 mg/kg	11.60 ± 1.69^***	63.95 ± 3.38^***	.000
MHAL	200 mg/kg	24.80 ± 3.15	19.17 ± 14.08	.093
MHAL	400 mg/kg	20.60 ± 2.16^**	32.43 ± 10.65^**	.006
EAHAL	200 mg/kg	23.33 ± 2.47^*	25.43 ± 10.96^*	.032
EAHAL	400 mg/kg	19.25 ± 2.29^**	34.76 ± 11.30^**	.004

All of the experimental values are denoted as mean ± SEM. MHAL = Methanol extract of Hemigraphis alternata leaves. EAHAL = Ethyl acetate extract of Hemigraphis alternata leaves. “^*푃 < 0.05, ^** 푃 < 0.01, ^*** 푃 < 0.001 versus control group (Dunnett’s test)”