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International Journal of Phytomedicine and Phytotherapy

Table 1 Protective effect of AIS on CCL4 induced elevation in hepatic enzymes, Bilirubin, TBARS content, and depletion of enzymatic and non enzymatic enzymes in Wistar rats

From: Hepatoprotective and antioxidant activity of Ipomoea staphylina Linn

Groups

SGOT (IU/L)

SGPT (IU/L)

ALP (IU/L)

Bilirubin (mg/dL)

TBARSa

GSHb

SODc

CATd

Group 1 (Normal Control)

52.42 ± 1.87d

36.65 ± 0.61d

90.86 ± 1.21c

0.67 ± 0.08c

6.02 ± 0.71c

24.60 ± 1.14a

23.00 ± 1.58a

57.20 ± 2.58a

Group 2 (Disease Control)

156.97 ± 1.84a

117.04 ± 6.21a

278.48 ± 0.74a

1.45 ± 0.11a

14.63 ± 1.08a

8.00 ± 1.58c

8.40 ± 1.14d

37.00 ± 1.58c

Group 3 (Silymarin)

59.50 ± 1.12c

46.54 ± 4.58bc

90.60 ± 4.27c

0.69 ± 0.06c

6.64 ± 0.33c

23.20 ± 3.03a

18.60 ± 1.14b

59.00 ± 1.58a

Group 4 (AIS 250 mg/kg b.w)

64.53 ± 5.60b

51.46 ± 7.56b

111.00 ± 9.05b

0.80 ± 0.02b

8.40 ± 1.14b

16.20 ± 1.92b

15.80 ± 1.30c

46.00 ± 4.30b

Group 5 (AIS 500 mg/kg b.w)

58.11 ± 0.77c

44.20 ± 4.43c

89.50 ± 8.66c

0.71 ± 0.05bc

5.68 ± 0.85c

24.80 ± 1.92ab

23.00 ± 2.23a

57.80 ± 2.77a

  1. Data are expressed as mean ± SD (n = 6)
  2. Mean values with different superscripts are significantly different from each other as revealed by Duncan post hoc test (P ≤ 0.05)
  3. ammoL/mg protein
  4. bμg of reduced glutathione / mg protein
  5. cU/mg of tissue
  6. dμmoL of H2O2 utilized/min/mg of protein