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International Journal of Phytomedicine and Phytotherapy

Table 4 Dose-response characteristics of the influence of Annona muricata ethyl acetate extracts on α-amylase activity

From: Possible anti-diabetic potentials of Annona muricata (soursop): inhibition of α-amylase and α-glucosidase activities

 

Dose-Response characteristics

Sigmoid plot interpolation characteristics

Hyperbola plot interpolation characteristics

Michaelis-Menten’s kinetics

Straight line regression interpolation characteristics

LogIC50

IC50

R2

Hill’s slope

Bmax

Kd

Km

Vmax

Y-intercept

slope

Fruit-pulp

0.341

2.196

1.000

4.412

44.75

−0.037

1.341 × 10−16

48.68

48.77

50.30

Leaf

0.503

3.186

1.000

2.003

46.33

−0.056

1.151 × 10−16

52.99

53.09

52.56

Stem-bark

0.644

4.409

1.000

1.892

45.13

−0.052

1.704 × 10−16

51.07

51.17

51.18

Root-bark

0.477

2.997

1.000

3.247

41.72

−0.033

1.275 × 10−16

45.00

45.08

47.18

Acarbose

0.236

1.722

1.000

1.481

51.17

−0.079

2.220 × 10−16

63.07

65.59

41.67

  1. Bmax = maximum binding capacity (U/L), Kd = dissociation constant (mg/dL), Km = Michaelis-Menten’s constant (mg/dL) and Vmax = maximum velocity (U/L)