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International Journal of Phytomedicine and Phytotherapy

Fig. 5 | Clinical Phytoscience

Fig. 5

From: Fruit juice of silverberry (Elaeagnus) and bayberry (Myrica) may help in combating against kidney dysfunctions

Fig. 5

Schematic representation showing role of gentamicin in the induction of nephrotoxicity and the role of phytocompounds from the three actinorhizal fruits showing activity to reduce the nephrotoxicity. Numbers beside Ø indicate the phytochemicals present in the three juices: 1 = γ-Sitosterol; 2 = n-Hexadecanoic acid; 3 = Octadecanoic acid; 4 = 1,2-Longidione. MAPK = mitogen activated protein kinase; TNF-α = tumor necrosis factor alpha; NFκβ = Nuclear factor kappa beta; TGF-β = Transforming growth factor beta; ICAM-1 = Intercellular cellular adhesion molecule-1; MCP-1 = Monocyte chemoattractant protein-1; O2 = Superoxide radical; OH = Hydroxyl radical; H2O2 = Hydrogen peroxide; NO = Nitric oxide; OONO = Peroxynitrate; ROS = Reactive oxygen species; RNS = Reactive nitrogen species

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