Aqueous garlic extract improves renal clearance via vasodilatory/antioxidant mechanisms and mitigated proteinuria via stabilization of glomerular filtration barrier

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 1 Experimental protocol and dose regimen

N = 30	Group description	10 days intraperitoneal administration	30 days oral administration	30 days recovery
Group 1 (n = 5)	Control	NS (2 ml/kg)	NS (2 ml/kg)	NS^a
Group 2 (n = 5)	Pb	Pb (35 mg/kg)^a	_	_
Group 3 (n = 5)	Pb + Recovery	Pb (35 mg/kg)	_	RP^a
Group 4 (n = 5)	Pb + 100 mg/kg AGE	Pb (35 mg/kg)	100 mg/kg AGE^a	_
Group 5 (n = 5)	Pb + 200 mg/kg AGE	Pb (35 mg/kg)	200 mg/kg AGE^a	_
Group 6 (n = 5)	Pb + 400 mg/kg AGE	Pb (35 mg/kg)	400 mg/kg AGE^a	_

N total number of rats, n number of rats per group, Pb lead, AGE aqueous garlic extract, NS normal saline, RP recovery period, ^apoint at which rats were sacrificed