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International Journal of Phytomedicine and Phytotherapy

Table 6 Effects of AGE on plasma and urine concentrations of creatinine, urea and total protein in Wistar rats with Pb-induced kidney injury

From: Aqueous garlic extract improves renal clearance via vasodilatory/antioxidant mechanisms and mitigated proteinuria via stabilization of glomerular filtration barrier

Plasma concentrationUrine concentration
Groups (n = 5)Creatinine (mg/dl)Urea (mg/dl)Total protein [×10−2 (mg/ml)]Creatinine (mg/dl)Urea (g/l)Total protein [×10−2 (mg/ml)]
[1] Control0.60 ± 0.0233.50 ± 0.7136.80 ± 0.5813.08 ± 0.28395.70 ± 7.2423.80 ± 0.58
[2] Pb1.24 ± 0.05a76.97 ± 2.25a13.60 ± 1.03a5.02 ± 0.54a202.60 ± 4.57a72.00 ± 1.64a
[3] Pb + Recovery1.16 ± 0.06a73.01 ± 1.48a19.20 ± 0.66ab5.81 ± 0.25a230.70 ± 14.95a69.20 ± 1.77a
[4] Pb + 100 mg/kg AGE0.63 ± 0.02bc58.32 ± 2.20abc28.40 ± 0.81abc9.06 ± 0.41abc300.60 ± 13.22abc29.40 ± 1.03abc
[5] Pb + 200 mg/kg AGE0.55 ± 0.02bc34.04 ± 0.81bcd35.20 ± 0.74bcd13.55 ± 0.27abc384.30 ± 18.24bcd22.00 ± 0.31bcd
[6] Pb + 400 mg/kg AGE0.54 ± 0.02bc31.09 ± 0.53bcd35.80 ± 0.92bcd13.98 ± 0.22abc422.60 ± 12.33bcd24.40 ± 0.68bcd
  1. Each value represents mean ± Standard Error of Mean (S.E.M.) at p < 0.05
  2. a = significantly different from control group [1],
  3. b = significantly different from Pb group [2],
  4. c = significantly different from Pb + recovery group [3], and
  5. d = significantly different from Pb + 100 mg/kg group [4]