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International Journal of Phytomedicine and Phytotherapy

Table 5 The effect of BNF-LCME on in vivo antioxidant parameters against D-Galactosamine induced hepatic damage in rats

From: Hepatoprotective studies on methanolic extract fractions of Lindernia ciliata and development of qualitative analytical profile for the bioactive extract

Groups

MDA

(mM/mg)

GSH

(nM/mg)

CAT

(U/mg)

Normal

1.44 ± 0.03

5.96 ± 0.190

10.36 ± 0.18

Toxic

3.92 ± 0.06

1.4 ± 0.03

3.41 ± 0.09

Silymarin 100 mg/kg

1.92 ± 0.04

(80.64%)

5.11 ± 0.23

(81.35%)

8.96 ± 0.11

(79.85%)

BNF-LCME 50

2.11 ± 0.16

(72.98%)

4.65 ± 0.08

(71.21%)

8.51 ± 0.56

(73.38%)

BNF-LCME 100

2.31 ± 0.14

(64.14%)

4.54 ± 0.11

(68.82%)

8.19 ± 0.16

(69.21%)

  1. Data expressed as mean ± SD, n = 6, values in parenthesis indicate percentage recovery
  2. p value- D-Galactosamine Vs vehicle; p value D-Galactosamine Vs treatments- * < 0.05; ** < 0.01; *** < 0.001
  3. BNF-LCME Butanone fraction of methanolic extract of Lindernia ciliata