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International Journal of Phytomedicine and Phytotherapy

Table 5 The effect of BNF-LCME on in vivo antioxidant parameters against D-Galactosamine induced hepatic damage in rats

From: Hepatoprotective studies on methanolic extract fractions of Lindernia ciliata and development of qualitative analytical profile for the bioactive extract

Groups MDA
(mM/mg)
GSH
(nM/mg)
CAT
(U/mg)
Normal 1.44 ± 0.03 5.96 ± 0.190 10.36 ± 0.18
Toxic 3.92 ± 0.06 1.4 ± 0.03 3.41 ± 0.09
Silymarin 100 mg/kg 1.92 ± 0.04
(80.64%)
5.11 ± 0.23
(81.35%)
8.96 ± 0.11
(79.85%)
BNF-LCME 50 2.11 ± 0.16
(72.98%)
4.65 ± 0.08
(71.21%)
8.51 ± 0.56
(73.38%)
BNF-LCME 100 2.31 ± 0.14
(64.14%)
4.54 ± 0.11
(68.82%)
8.19 ± 0.16
(69.21%)
  1. Data expressed as mean ± SD, n = 6, values in parenthesis indicate percentage recovery
  2. p value- D-Galactosamine Vs vehicle; p value D-Galactosamine Vs treatments- * < 0.05; ** < 0.01; *** < 0.001
  3. BNF-LCME Butanone fraction of methanolic extract of Lindernia ciliata