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International Journal of Phytomedicine and Phytotherapy

Table 5 Results of the anti-inflammatory activity of the total ethanol extract and the different fractions of C. myxa L. leaves using carrageenan-induced paw edema method

From: Total phenolic and flavonoid contents and antioxidant, anti-inflammatory, analgesic, antipyretic and antidiabetic activities of Cordia myxa L. leaves

Group Thickness of the paw (mm)
0 h 30 min 1 h 2 h 3 h 4 h 5 h
Control (−ve) 7.38 ± 0.25 7.25 ± 0.29 7.25 ± 0.29 7.63 ± 0.25 7.75 ± 0.29 7.75 ± 0.29 7.75 ± 0.29
Total extract (350 mg/kg) 7.25 ± 0.29 7.00 ± 0.00 6.50 ± 0.41 * 6.25 ± 0.29 *** 6.00 ± 0.41 *** 6.25 ± 0.29 *** 6.75 ± 0.29 **
Petroleum ether fraction (350 mg/kg) 7.25 ± 0.29 7.13 ± 0.25 6.88 ± 0.25 6.75 ± 0.29 *** 6.63 ± 0.48** 6.38 ± 0.25 *** 7.13 ± 0.25 *
Dichloromethane fraction (350 mg/kg) 7.00 ± 0.00 * 7.00 ± 0.00 6.38 ± 0.48 * 5.75 ± 0.29 *** 4.63 ± 0.75 *** 4.25 ± 0.29 *** 5.63 ± 0.48 ***
Ethyl acetate fraction (350 mg/kg) 7.38 ± 0.25 7.13 ± 0.25 6.63 ± 0.48 6.13 ± 0.48 ** 5.50 ± 0.41 *** 4.63 ± 0.48 *** 6.00 ± 0.41 ***
Butanol fraction (350 mg/kg) 7.25 ± 0.29 7.13 ± 0.25 6.75 ± 0.29 * 6.50 ± 0.41 ** 6.38 ± 0.25 *** 5.755 ± 0.29 *** 6.50 ± 0.41 **
Indomethacin (8 mg/kg) 7.25 ± 0.29 6.88 ± 0.25 5.25 ± 0.65 *** 3.88 ± 0.25 *** 3.75 ± 0.29 *** 3.75 ± 0.29 *** 5.75 ± 0.29 ***
  1. The results are presented as the mean ± S.E.M. (Standard error of the mean). Differences with respect to the control group were calculated using the student’s T-test (*P > 0.05, **P < 0.01, ***P < 0.001)