International Journal of Phytomedicine and Phytotherapy
Group | Thickness of the paw (mm) | ||||||
---|---|---|---|---|---|---|---|
0 h | 30 min | 1 h | 2 h | 3 h | 4 h | 5 h | |
Control (−ve) | 7.38 ± 0.25 | 7.25 ± 0.29 | 7.25 ± 0.29 | 7.63 ± 0.25 | 7.75 ± 0.29 | 7.75 ± 0.29 | 7.75 ± 0.29 |
Total extract (350 mg/kg) | 7.25 ± 0.29 | 7.00 ± 0.00 | 6.50 ± 0.41 * | 6.25 ± 0.29 *** | 6.00 ± 0.41 *** | 6.25 ± 0.29 *** | 6.75 ± 0.29 ** |
Petroleum ether fraction (350 mg/kg) | 7.25 ± 0.29 | 7.13 ± 0.25 | 6.88 ± 0.25 | 6.75 ± 0.29 *** | 6.63 ± 0.48** | 6.38 ± 0.25 *** | 7.13 ± 0.25 * |
Dichloromethane fraction (350 mg/kg) | 7.00 ± 0.00 * | 7.00 ± 0.00 | 6.38 ± 0.48 * | 5.75 ± 0.29 *** | 4.63 ± 0.75 *** | 4.25 ± 0.29 *** | 5.63 ± 0.48 *** |
Ethyl acetate fraction (350 mg/kg) | 7.38 ± 0.25 | 7.13 ± 0.25 | 6.63 ± 0.48 | 6.13 ± 0.48 ** | 5.50 ± 0.41 *** | 4.63 ± 0.48 *** | 6.00 ± 0.41 *** |
Butanol fraction (350 mg/kg) | 7.25 ± 0.29 | 7.13 ± 0.25 | 6.75 ± 0.29 * | 6.50 ± 0.41 ** | 6.38 ± 0.25 *** | 5.755 ± 0.29 *** | 6.50 ± 0.41 ** |
Indomethacin (8 mg/kg) | 7.25 ± 0.29 | 6.88 ± 0.25 | 5.25 ± 0.65 *** | 3.88 ± 0.25 *** | 3.75 ± 0.29 *** | 3.75 ± 0.29 *** | 5.75 ± 0.29 *** |