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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of EETI on formalin induced writhing effect in mice

From: In vivo and in vitro pharmacological activities of Tacca integrifolia rhizome and investigation of possible lead compounds against breast cancer through in silico approaches

Groups

Dose mg/kg BW

Mean ± SEM (% Writhing)

1st phase (0–5 min)

%inhibition 1st phase (0–5 min)

Mean ± SEM (%Writhing) last phase (15–30 min)

%inhibition last phase (15–30 min)

Control

56.6 ± 0.93

40.4 ± 1.03

Diclofenac sodium

10

14.90 ± 0.81***

73.67

13.60 ± 0.51***

66.56

EETI

200

32.6 ± 0.24***

42.40

23.80 ± 0.20***

41.09

EETI

400

20.8 ± 0.86***

63.25

20.75 ± 0.72***

48.63

  1. SEM standard error of mean, n = 5, where n is the number of mice, % percentage. Values in the table are expressed as mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001 significantly different in comparison with control