In-vivo and in-vitro evaluation of pharmacological activities of Ardisia solanacea leaf extract

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of methanolic extract of A. solanacea on Open-field test apparatus while test session

Test groups	Number of squares visited (Mean ± SEM)
Test groups	0 min	30 min	60 min	90 min	120 min
Control	85.2 ± 0.58	75.0 ± 0.70	71.2 ± 1.16	68 ± 0.701	62 ± 0.70
Standard	77.0 ± 0.70^##	39.6 ± 0.51^##	23.8 ± 0.86^##	16 ± 0.70^##	10 ± 0.701^##
ASME 200	84.6 ± 0.51	51.0 ± 0.70^##	32.2 ± 1.07^##	26 ± 0.70^##	22 ± 0.701^##
ASME 400	83.2 ± 0.86	45.6 ± 1.03^##	29.0 ± 0.70^##	21.2 ± 0.80^##	18.8 ± 0.66^##
ASNH 200	87.6 ± 1.03	59.2 ± 1.07^***	39.6 ± 1.28^##	32 ± 1.23^##	27.6 ± 1.07^##
ASNH 400	84.6 ± 0.68	54.8 ± 0.86^##	34.8 ± 0.74^##	26.8 ± 0.86^##	25.8 ± 0.86^##
ASCF 200	80.6 ± 0.50^*	45.4 ± 0.93^##	30.6 ± 0.93^##	25 ± 0.70^##	22.6 ± 0.51^##
ASCF 400	83 ± 1.00	44 ± 1.14^##	26.6 ± 0.51^##	21 ± 0.70^##	19.4 ± 0.50^##
ASCC 200	83.8 ± 1.07	50 ± 0.70^##	38.2 ± 1.16^##	32.4 ± 0.75^##	28.4 ± 0.75^##
ASCC 400	81.8 ± 1.90	44 ± 1.73^##	34.2 ± 0.58^##	28 ± 1^##	26 ± 0.84^##

Note: Each value represents the mean ± SEM. (n = 5). One- way ANOVA followed by Dunnett’s t test. ##p < 0.005, *p < 0.05 compared with control. ASME = methanolic Extract of A. solanacea, ASNH = n-hexane soluble fraction, ASCF = chloroform soluble fraction, ASCC = carbon tetrachloride soluble fraction