In-vivo and in-vitro evaluation of pharmacological activities of Ardisia solanacea leaf extract

Table 5 Effect of methanolic extract of Ardisia solanacea on Hole-crossed test apparatus while test session

Test groups	Number of hole crossed (Mean ± SEM)
Test groups	0 min	30 min	60 min	90 min	120 min
Control	20 ± 0.70	19.2 ± 1.74	18.4 ± 1.54	18.2 ± 1.39	15.2 ± 0.58
Standard	19 ± 0.71	8.4 ± 1.37^##	5.8 ± 0.74^##	4.4 ± 0.93^##	3.2 ± 0.58^##
ASME 200	20.8 ± 0.58	10.4 ± 0.68^##	7.8 ± 0.37^##	5.2 ± 0.58^##	3.4 ± 0.68^##
ASME 400	21.8 ± 0.86	9.8 ± 0.74^##	7.6 ± 0.40^##	4.6 ± 0.40^##	3.2 ± 0.49^##
ASNH 200	21.2 ± 1.02	13.4 ± 0.51^##	9.80 ± 0.74^##	7.2 ± 0.37^##	4.6 ± 0.51^##
ASNH 400	23.4 ± 0.93	11.4 ± 0.51^##	7.6 ± 0.51^##	5.8 ± 0.37^##	4.2 ± 0.58^##
ASCF 200	20.6 ± 0.93	10.2 ± 0.80^##	7.2 ± 0.37^##	5 ± 0.55^##	3.2 ± 0.66^##
ASCF 400	22.6 ± 1.75	10.2 ± 1.16^##	7.6 ± 1.55^##	4.8 ± 1.12^##	3.2 ± 1.02^##
ASCC 200	24.2 ± 1.77	21.8 ± 1.59	21.4 ± 1.47	22.2 ± 1.36	20.6 ± 1.83^*
ASCC 400	22.8 ± 1.96	20.6 ± 2.12	18.4 ± 1.64	17.2 ± 1.63	16.4 ± 1.20

Note: Each value represents the mean ± SEM. (n = 5). One- way ANOVA followed by Dunnett’s t test. ^##p < 0.005, *p < 0.05 compared with control. ASME = Methanolic Extract of A. solanacea, ASNH = n-hexane soluble fraction, ASCF = Chloroform soluble fraction, ASCC = Carbon-tetrachloride soluble fraction